Can’t open any program (even in safe mode)

I have a problem with the cursor mouse on my laptop, I can’t seem to open any program with it. Can not open anything in networking safe mode either. I have a lot of important things stored, can anyone tell me why this might be happening?

Hey there!
Try this
In the search box, type file explorer options > at the pop up box, click File Explorer Options > click View at the top > under Click items as follows heading, put a dot at the option you want > OK when done.

Hello @Spencer
Welcome to community!:bouquet:
step -1 Did you check any other software or any other file?
step -2 Did you use “enter” key on keypad
and i want to know that why are you using safe mode to open file while you can boot in normal mode