Create a Dynamic Distribution list on onprem

At the moment, I am using exchange 2010 hybrid environment and I am quite new to it. I want to create a Dynamic Distribution list on onprem. I also want it moved to cloud. I know that I can create these lists from admin centre and that I can create groups from portal.office.com. What are the main differences between these two things, as I know little about them at the moment?

Hello
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