This upgrade path is not supported please close setup and re-launch from the root of the media or go back and pick a different installation choice

Hi @Carissa,

How you are performing your Windows 10 upgrade? If you are using USB media or external drive, then make sure all the Windows 10 media files are located on the root drive. To avoid this type of error while performing the Windows 10 upgrade or fresh install always create a bootable drive. For the clear explanation, please follow the below article on how to create a Windows 10 bootable drive and perform Windows 10 upgrade.

Hope this help